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Depression Grand Challenge

UCLA is opening the door to hope for millions, including someone you know.

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An Unprecedented Approach to Helping Everyone Thrive

A big problem is also a big opportunity, a chance to change life for the better. Or, in the case of the UCLA Depression Grand Challenge, a chance to change life for well-being.

Depression is the world’s greatest health problem. Consider these statistics: Three hundred million people globally suffer from depression. In the U.S. alone, the disease costs more than $210 billion in medical expenses, long-term care, and lost productivity. It knows no boundaries, affecting those of all generations, genders, ethnicities, and socioeconomic circumstances. And it is the strongest risk factor for suicide—one million people commit suicide each year. Perhaps you have lost someone you love in this devastating way.

And treatment? Fifty percent of those treated for depression remain depressed. UCLA knows something needs to change. Now the university is leading the way with a collaborative effort that engages campus and community partners to apply ingenious research and technology and hands-on, eyes-and-ears-open care to cure depression and close the door on this epidemic.

UCLA is ideally suited to spread hope around the world to people and their families struggling with depression. Like California itself, the university is home to fearless pioneers, innovators, bold thinkers, and optimists. This effort, according to faculty expert Dr. Michelle Craske, “is unheard and massive and wonderful.” It’s also costly. But not nearly as costly as the status quo if it means helping someone you know.

“This project is a safety net and a lifesaver,” says Laurie Gordon, a member of the Depression Grand Challenge leadership council. “With proper funding, it can be those things on a very large scale.”

Every gift, including yours, opens the door to hope for humans like you and those you love.

  • Two young men in t-shirts, one of which says "Out Depression"

    UCLA is raising awareness and hope by bringing depression out of the dark.

  • Image of a mouse hippocampus

    Neuroscientists study how the brain works to discover the best treatments for depression.

  • close-up shot of a smartphone in a woman's hand

    New technologies may help people with diagnosis and treatment, no matter where they are.

  • Diagram contrasting current treatment pattern with development of a personalized health treatment

    The DGC uses technology to identify, monitor, and assess treatment for those at risk.

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“This project is a safety net and a lifesaver. With proper funding, it can be those things on a very large scale.”
Laurie Gordon Depression Grand Challenge Leadership Council Member
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Depression is a terrible disease that needs to be better understood....
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